كتابة النص: الأستاذ الدكتور يوسف أبو العدوس - جامعة جرش قراءة النص: الدكتور أحمد أبو دلو - جامعة اليرموك مونتاج وإخراج : الدكتور محمد أبوشقير، حمزة الناطور، علي ميّاس تصوير : الأستاذ أحمد الصمادي الإشراف العام: الأستاذ الدكتور يوسف أبو العدوس
فيديو بمناسبة الإسراء والمعراج - إحتفال كلية الشريعة بجامعة جرش 2019 - 1440
فيديو بمناسبة ذكرى المولد النبوي الشريف- مونتاج وإخراج الدكتور محمد أبوشقير- كلية تكنولوجيا المعلومات
التميز في مجالات التعليم والبحث العلمي، وخدمة المجتمع، والارتقاء لمصاف الجامعات المرموقة
محليا واقليميا وعالميا.
المساهمة في بناء مجتمع المعرفة وتطوره من خلال إيجاد بيئة جامعية، وشراكة مجتمعية محفزة للابداع،
وحرية الفكر والتعبير، ومواكبة التطورات التقنية في مجال التعليم، ومن ثم رفد المجتمع بما يحتاجه من
موارد بشرية مؤهلة وملائمة لاحتياجات سوق العمل.
تلتزم الجامعة بترسيخ القيم الجوهرية التالية:
الإلتزام الإجتماعي والأخلاقي، الإنتماء،العدالة والمساواة، الإبداع، الجودة والتميّز، الشفافية والمحاسبة، الحرية المنظبطة والمستقبلية.
BSC, Master , Assistant Prof , Associate Prof
21 year of exprience
ABSTRACT This research was performed by a clinical pharmacist to determine the efficacy of dexmedetomidine as an alternative therapy in laparoscopic appendectomy surgery for acute and short-lived analgesic appendicitis and to focus on the consistency of pharmacotherapy and patient safety. A randomized, double-blind, prospective analysis of 2 groups allocated to the fentanyl [GF] and fentanyl dexmedetomidine [GF-D] groups. Propofol, Sevoflurane, Atracurium, and intraoperative fentanyl bolus were administered to the patient, followed by an infusion of maintenance dose of 0.2 μg/kg/h for the two grades. GF patients were given placebo, however, while patients with GF-D received both dexmedetomidine and fentanyl as an infusion (0.5 μg/kg/h). The requirements for postoperative analgesics and the need for initial postoperative analgesics, consistency of hemodynamic parameters, side effects of nausea and vomiting, and food tolerance have been controlled. GF-D showed lower side effects and food resistance compared to GF: pain score, morphine consumption, nausea, and vomiting (p<0.05), When GF was compared to GF-D, the period for the first postoperative morphine was shorter in GF (p<0.05). The addition of dexmedetomidine to appendectomy surgery is strongly recommended; clinical pharmacist involvement has improved patient safety and avoids any adverse drug reaction.
A The majority of people around the world experience the effects of the inadequacy of vitamin B12. A cross-sectional study was carried out at the beginning of April to end of December 2019, to examine the impact of vitamin B12 inadequacy and its treatment in improving total cholesterol, low-density lipopro-tein (LDL), high-density lipoprotein (HDL) and triglyceride (TG). The data that contains the levels of vitamin B12, lipid parameters (total cholesterol, LDL, HDL and TG) were gathered from 400 patients (n =400) from various clinical research centres situated in the capital of Jordan, Amman. The patient's samples were classi ied into multiple age groups. The data of both total cholesterol and LDL levels were gathered from thirty-ive (n=35) patients, their age group is between 55-66 and have begun treatment of vitamin B12 de iciency by intramuscular infusion (1.0 mg) of vitamin B12. Almost 20.5% of the studied individuals (n=400) are found to be vitamin B12 de icient, as the level of vitamin B12 was equal to (<190 ng/ml). The age group (56-66) years old was found to have a signi icant decrease in vitamin B 12 (p< 0.01) and this results was associated with a critical increment in the levels of both total cholesterols (p < 0.01) and LDL p< 0.02) on contrast with other age groups. Our results did not reveal any signi icant changes in the levels of other lipid parameters in all age groups. Intramuscular injection treatment for thirty days reduces signi icantly (p< 0.01) the level of vitamin B12. This treatment strategy leads to a decrease in both total cholesterols (p< 0.01) and LDL levels (p< 0.01) substantially .
Aim: Lumbar foraminotomy surgery requires a potent opioid with short duration and rapid onset of action. In the present study we intended to compare the efficacy of fentanyl alone vs the combination of dexmedetomidine and fentanyl during lumbar foraminotomy surgery. Methods: The duration and requirements for first postoperative analgesics, hemodynamic stability, and respective side effects were studied. A prospective, randomized, double blind study of 40 patients (fentanyl group [Fen group] and fentanyl-dexmedetomidine group [Fen-Dex group], n=20 each) scheduled for lumbar foraminotomy surgery under pharmaceutical care intervention was carried out. Patients were classified as class I or II, according to the American Society of Anesthesiologists physical status classification. Patients received intraoperative propofol, sevoflurane, atracurium, and either fentanyl loading dose of 1.0 μg/kg and maintenance infusion dose of 0.2 μg/kg/h in both groups. The patients of the Fen group received normal saline (0.9%) placebo, while the patients of the Fen-Dex group received dexmedetomidine infusion (0.5 μg/kg/h) along with the fentanyl infusion. Postoperative morphine doses were given. Hemodynamic stability, pain, postoperative analgesia requirement, side effects of drugs, and other effects were monitored. Results: In the Fen-Dex group, the pain score was significantly less than in the Fen group (p<0.05). The time to first postoperative analgesia request was prolonged in the Fen-Dex group compared to the Fen group. On the other hand, requirement of morphine, and postoperative symptoms and episodes of nausea and vomiting were significantly greater in the Fen group than in the Fen-Dex group (p<0.05). Conclusion: The present study suggests the addition of dexmedetomidine during lumbar foraminotomy surgery at different levels would be beneficial to reduce morphine consumption and any adverse drug reaction.
Abstract: This study was performed to evaluate the efficacy of dexmedetomidine on postoperative pain, analgesics consumption, time for first request of analgesia and the hemodynamic stability 24 h after laparoscopic myomectomy surgery. Sixty patients undergoing double-blind placebo-controlled myomectomy laparoscopic surgery were assigned randomly to 2 groups to be administered either dexmedetomidine as a loading of 1 µg/kg for 10 min followed by a maintenance infusion of 0.5 µg/kg/h (DEX group, n = 30), or a normal saline infusion (CTRL group, n = 30). In a 24 h recovery period, in a post anesthesia care unit (PACU) the first pain score, analgesic requirements, total operation time and the hemodynamic control were measured and observed. Postoperative pain scores and analgesics intake were significantly higher in the normal saline CTRL group comparing to DEX group (p < 0.05). Time needed for first request of analgesia was significantly shorter in the normal saline CTRL group comparing to dexmedetomidine DEX group (p < 0.05), while the hemodynamic measurements were satisfactory and normal in both groups. Intra-operative dexmedetomidine infusion reduces postoperative pain in the first 24 h for patients undergoing myomectomy laparoscopy while providing an ideal hemodynamic stability. Dexmedetomidine could be an adjunct therapy to reduce the postoperative analgesics consumption during myomectomy surgery. Keywords: dexmedetomidine, myomectomy laparoscopy, postoperative pain, hemodynamic stability
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Background: Pain control in pediatric patients undergoing tonsillectomy remains a dilemma. Tramadol and ketamine are reported to be an effective analgesic. Aim of the study: To evaluate the effect of peritonsillar infiltration of tramadol in combination with ketamine versus peritonsillar infiltration of tramadol posttonsillectomy. Setting: Specialty hospital in Jordan. Method: Sixty children, aged 7-12 years, selected for tonsillectomy were enrolled in the study. We divided the patients into two groups 30 of each, Group I: received peritonsillar saline and peritonsillar infiltration of tramadol 2 mg/kg, Group II: received peritonsillar infiltration of ketamine 1.0 mg/kg added to peritonsillar tramadol 2 mg/kg. Main outcome measure: Hemodynamic stability, pain scale, first request of analgesia, total analgesics consumption and post-operative nausea and vomiting (PONV) side effects were recorded 24 h after surgery. Results: The analysis of data showed that Group II had significantly lower face pain scale, longer time for first request of analgesia, and better hemodynamic stability than GI (p < 0.001). On the other hand the total analgesics requirements, time of surgery, and PONV showed no significant differences between the two groups. Conclusion: Combined use of peritonsillar infiltration of ketamine 1.0 mg/kg with tramadol 2 mg/kg provided prolong analgesic effects, less pain with no side effect, and better hemodynamic stability compared with using tramadol alone in patients undergoing tonsillectomy.
Abstract Aim: The hypothesis that postoperative pain would be reduced by using 1 lg/kg/min of ketamine, both intra- and post-operatively, for lumbar microdiscectomy surgery was assessed by measuring morphine consumption. Patient side effects were reported. Methods: Forty-five patients undergoing microdiscectomy surgery were randomized under double-blind conditions into three groups: Group1 (G1) received normal saline, Group 2 (G2) ketamine (1 lg/kg/min) intra-operatively and Group 3 (G3) ketamine (1 lg/kg/min) both intra- and postoperatively. Morphine consumption, pain scores, nausea and vomiting, CNS disorders were recorded for 24 h post surgery. This study was conducted by applying the concept of a clinical pharmacist intervention. Results: The time for the first analgesia demand dose was significantly shorter (P < 0.05) in G117 ± 1.7 min than for G2 and G3. In G3 morphine consumption 6, 12, and 24 h after surgery was 3 ± 2.26, 9.2 ± 2.11 and 26.9 ± 2.71 mg. Total morphine consumption was significantly lower for G3 than for G1 or G2 (P < 0.05). The visual analog scale score (VAS) values were significantly lower in G3 (P < 0.05) than for the other groups during the first 24 h. The rate of nausea and vomiting was significantly higher in G1 vs G3 (P < 0.05). No difference in drug induced CNS disturbances was observed among the groups. Conclusions: Using 1 lg/kg/min of ketamine hydrochloride intra- and post-operatively for microdiscectomy surgery could be an adjunct therapy to reduce postoperative morphine consumption minimizing its side effects.
Ab stract. Aim: This study is aimed at con duct ing a pro gram for two differ ent an es - thetic meth ods used during a spi nal fu sion surgery to en sure better intraoperative hemo - dynamic sta bil ity and post-op er a tive pain con - trol. Meth ods: A pro spec tive, ran dom ized, dou ble blind study in pa tients sched uled for spi nal fu sion surgery, who were ran domly al - lo cated to two groups, G1 and G2, (n = 15 per group), class I – II ASA, was car ried out. Both groups re ceived pre-op er a tively midazolam, fol lowed intra-op er a tively by propofol, sevo - flurane, atracurium, and either remifentanil in fu sion 0.2 µg/kg/min (G1), or the same dose of remifen tanil in fu sion and low doses of ketamine in fu sion 1 µg/ kg/min (G2) an es - thet ics, an ti dote med i ca tion and post op er a - tive mor phine doses. HR, MAP, vi tal signs, sur gi cal bleed ing, urine out put, du ra tion of sur gery and du ra tion of an es the sia were re - corded. In a 24 h re cov ery pe riod in a post-an - es the sia care unit (PACU) the re cov ery time, the first pain score and anal ge sic re quire - ments were mea sured. Re sults: Intra-op er ative HR and ar te rial BP were sig nifi cantly less (p < 0.05) in G1 as compared to G2. In the PACU the first pain scores were signifi cantly less (p < 0.05) in G2 than in G1. The time for the first pa tient an al ge sia de mand dose was greater in G2, as also mor phine con sump tion which was greater in G1 than G2 (p < 0.05). Other re sults were the same. None of the pa - tients had any ad verse drug re ac tion. Con clu - sions: Add ing low doses of ketamine hy dro - chlo ride could be a rou tine ther apy to improve the hemodynamic sta bil ity and re duce the post op er a tive mor phine con sump tion dur ing spi nal fu sion sur gery.
'is randomized prospective clinical study aimed to investigate the effects of dexmedetomidine or ketamine administration to total intravenous anesthesia (TIVA) on postoperative analgesia in subjects undergoing elective laparoscopic cholecystectomy procedures. 90 adults, American Society of Anesthesiologists (ASA) physical status 1 and II patients, who underwent elective laparoscopic cholecystectomy procedures were included in the study and randomized into three groups equally. Remifentanil, propofol, and rocuronium infusions were used for TIVA guided by the bispectral index. In group KETA, 10 μg/kg/min ketamine was added to TIVA before surgery, and in group DEX, 0.5 μg/kg/h dexmedetomidine was added to TIVA before surgery. Normal saline infusions were infused in the control group. Postoperative analgesia was provided with intravenous patient-controlled analgesia (PCA) morphine (1 mg bolus morphine, 5 min lockout time). Hemodynamic parameters, scores of visual analogue scale (VAS) for pain, rescue morphine requirements, and side effects such as sedation, nausea, and vomiting were recorded for 48 hours after surgery. Postoperative first analgesic requirement time was longer in group KETA (P < 0.001), and it was longer in group DEX than in the control group (P < 0.001). Pain scores were lower in group KETA and group DEX than in the control group at all corresponding times throughout the 48 h period of observation. Intravenous PCA morphine consumptions were higher in the control group than in group KETA (P < 0.001 for all followed-up times), and they were higher in group DEX than in group KETA (P < 0.001 for all followed-up times). It is concluded that the use of dexmedetomidine or ketamine infusions can be suitable as an additive for TIVA in the intraoperative period. Furthermore, the addition of both drugs to the TIVA protocol may improve postoperative pain relief and decrease opioid consumption.
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